abstract：:Intracellular recordings were made from neurons in bullfrog sympathetic ganglia. Orthodromic, intracellular and antidromic stimulations evoked recurrent depolarizing responses accompanied by a spontaneous firing of the action potential in type 2 neurons. The depolarizing response elicited by intracellular and antidrom...

journal_title：Neuroscience letters

authors： Nishimura T,Akasu T

更新日期：1988-04-12 00:00:00

abstract：:The circadian rhythm and dehydration-induced response of vasopressin (AVP) levels in rat cerebrospinal fluid (CSF) were studied after lesions had been made in the paraventricular (PVN) and suprachiasmatic (SCN) nuclei. The rhythmic fluctuation of AVP levels in CSF was abolished after SCN lesions, whereas lesions of th...

journal_title：Neuroscience letters

authors： Jolkkonen J,Tuomisto L,van Wimersma Greidanus TB,Riekkinen PJ

更新日期：1988-03-31 00:00:00

abstract：:Dopaminergic neurons of the goldfish retina were selectively destroyed after a single intravitreal injection of 1-methyl-4-phenylpyridinium ion (MPP+). The ultrastructural analysis of the retina 3 days after toxin administration shows darkening of some retinal neurons present in the inner nuclear layer including their...

journal_title：Neuroscience letters

authors： Villani L,Poli A,Bissoli R,Barnabei O

更新日期：1988-03-31 00:00:00

abstract：:Using the Golgi silver impregnation technique the present study examines the morphology and development of presumptive local circuit neurons in lamina III of the rat lumbar spinal cord. These neurons generate local axonal plexuses which remain within the gray matter and dendritic trees which arborize in lamina III and...

journal_title：Neuroscience letters

authors： Beal JA,Russell CT,Knight DS

更新日期：1988-03-21 00:00:00

abstract：:A new method for on-line analysis of in vivo differential normal pulse voltammograms is reported. They are fitted by least squares to an expression describing the contribution of different electroactive species and the baseline. Its validity for resolving ascorbate (AA), dopamine (DA) and DOPAC signals is evidenced by...

journal_title：Neuroscience letters

authors： Gonzalez-Mora JL,Sanchez-Bruno JA,Mas M

更新日期：1988-03-21 00:00:00

abstract：:In human caudate and cortex membranes, [3H]serotonin ([3H]5-HT) labels 5-HT1A and 5-HT1C recognition sites which show nanomolar affinity for 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)-tetralin) and mesulergine respectively, whereas no 5-HT1B binding could be identified. However, the majority of the sites labelled by [3...

journal_title：Neuroscience letters

authors： Hoyer D,Waeber C,Pazos A,Probst A,Palacios JM

更新日期：1988-03-10 00:00:00

abstract：:Following iontophoretic injections of the retrograde tracer Fluoro-gold into the rat locus coeruleus (LC), retrogradely labeled neurons were seen predominantly in the area of C1 adrenergic neurons in the ventrolateral medulla (nucleus paragigantocellularis; PGi) and in the area of C3 adrenergic neurons in the dorsomed...

journal_title：Neuroscience letters

authors： Pieribone VA,Aston-Jones G,Bohn MC

更新日期：1988-03-10 00:00:00

abstract：:The central cardiovascular effects of neuropeptide Y (NPY) have been investigated by microinjection of the peptide into the hypothalamic paraventricular nucleus (PVN) of conscious rats. NPY (100 ng) elicited a significant bradycardia in both Long Evans (control) rats (-27 +/- beats/min) and vasopressin-deficient Bratt...

journal_title：Neuroscience letters

authors： Harland D,Bennett T,Gardiner SM

更新日期：1988-02-29 00:00:00

abstract：:Carbonic anhydrase (CA) activity was localized histochemically in the retina and brain of the honeybee drone. A positive reaction that could be inhibited with 10(-5) M acetazolamide was found only in brain glial cells such as those in the lamina and medulla of the optic lobes. In the retina, neither the photoreceptors...

journal_title：Neuroscience letters

authors： Walz B

更新日期：1988-02-15 00:00:00

abstract：:Recently we have demonstrated the presence of a gap in the avian retinotectal projection, that corresponds with the locus of retinotopic representation of the elongated optic nerve head. The present report describes an equivalent gap in the optic neuropiles of the avian ventral geniculate nucleus and griseum tectalis ...

journal_title：Neuroscience letters

authors： Puelles L,Martinez S,Martinez-de-la-Torre M

更新日期：1988-02-15 00:00:00

abstract：:Prolonged exposure of hippocampal slices to L-glutamate was found to produce a biphasic effect on excitatory synaptic transmission from Schaffer collateral-commissural fibers to CA1 pyramidal neurons: an early blockade of postsynaptic responses was followed by a progressive recovery. Antagonists of N-methyl-D-aspartat...

journal_title：Neuroscience letters

authors： Krishtal OA,Smirnov SV,Osipchuk YuV

更新日期：1988-02-15 00:00:00

abstract：:Three forms of stress-induced analgesia (electric shock, forced water-swim and novelty) were used to examine the nature of the endogenous antiopiate system. It was hypothesized that a role of the antiopiate system may be to regulate the extent of antinociception within varying environments. The antiopiate properties o...

journal_title：Neuroscience letters

authors： Galina ZH,Kastin AJ

更新日期：1988-02-03 00:00:00

abstract：:The pharmacokinetics of 2-amino-7-phosphonoheptanoate (AP7) in rat plasma and appearance in cerebrospinal fluid (CSF) are reported. Using high-performance liquid chromatography (HPLC) with fluorescence detection, concentrations of AP7 can be detected as low as 1.0 microM. Peak CSF concentrations (12-15 microM) for bot...

journal_title：Neuroscience letters

authors： Compton RP,Hood WF,Monahan JB

更新日期：1988-02-03 00:00:00

abstract：:The uptake of 2-deoxy-[14C]glucose (2-DG) by motor neurons in adult rat hypoglossal nuclei was studied 3 days after subepineural injection of 'crude' soluble protein extracts from intact and injured peripheral nerves into normal hypoglossal nerves. Injured nerve extracts were obtained from 'proximal' and 'distal' segm...

journal_title：Neuroscience letters

authors： Singer PA,Mehler S,Fernandez HL

更新日期：1988-01-22 00:00:00

abstract：:The electromyographic responses elicited in the first dorsal interosseus muscle by small muscle stretches or by electrical stimulation of the median nerve were investigated in parkinsonian patients and in age-matched healthy subjects. Stimuli were applied during a steady level of contraction in the intrinsic hand musc...

journal_title：Neuroscience letters

authors： Noth J,Schürmann M,Podoll K,Schwarz M

更新日期：1988-01-22 00:00:00

abstract：:The N-methyl-D-aspartate (NMDA) receptor blocker 2-amino-5-phosphonovaleric acid [+/-)-2-APV) and kynurenic acid both suppressed spontaneous epileptiform burst discharges in the CA3 region of rat hippocampal slices. When the bursts were induced by perfusion with magnesium-free medium (+/-)-2-APV was the more potent in...

journal_title：Neuroscience letters

authors： Stone TW

更新日期：1988-01-22 00:00:00

abstract：:The cellular location of kappa-opioid binding sites in the guinea pig cerebellum has been investigated. kappa-Opioid sites were labelled using [3H]ethylketocyclazocine in the presence of mu- and delta-blocking ligands. In vitro autoradiography demonstrated that this kappa-opioid binding was localized predominantly in ...

journal_title：Neuroscience letters

authors： Bunn SJ,Wilkin GP

更新日期：1988-01-11 00:00:00

abstract：:Following injections of horseradish peroxidase into the mediodorsal thalamic nucleus (MD), retrogradely labeled cells were found in various areas in the cat and rabbit. Among these, olfactory-related areas to which the olfactory bulb projects directly or indirectly via the piriform cortex were the olfactory tubercle, ...

journal_title：Neuroscience letters

authors： Motokizawa F,Yasuda N,Shimomura F

更新日期：1988-01-11 00:00:00

abstract：:Respiration can be automatic or controlled behaviorally. Behavioral control in the cat occurs, at least in part, through control of the brainstem respiratory neurons that constitute the automatic system. Thus, when inspiration is inhibited behaviorally, inspiratory neurons in the medulla are inactivated. Reported here...

journal_title：Neuroscience letters

authors： Orem J

更新日期：1987-12-29 00:00:00

abstract：:We studied axonal branching of 14 parabrachial nucleus neurons, activated antidromically from 2 of the 3 stimulation sites, i.e. the ipsi- and contralateral thalamic taste area (TTAs) and the ipsilateral central nucleus of the amygdala (CA). Making use of antidromic latencies, collision times and refractory periods at...

journal_title：Neuroscience letters

authors： Hayama T,Ogawa H

更新日期：1987-12-16 00:00:00

abstract：:Evidence, based on voltage-clamp and current-clamp recording, is presented for endogenous receptors for vasoactive intestinal polypeptide (VIP) on the cell membrane of the Xenopus oocyte. At normal resting potential a hyperpolarisation is produced by VIP, associated with an increase in K+ conductance. The response is ...

journal_title：Neuroscience letters

authors： Reale V,Ashford ML,Barnard EA

更新日期：1987-12-16 00:00:00

abstract：:Copper, manganese and zinc were measured by flameless atomic absorption spectrophotometry in the developing brain of normal and quaking mice. The latter is a neurological mutant presenting early arrest of myelination. Copper concentration was increased by 200% between 10 and 20 days after birth and then leveled off in...

journal_title：Neuroscience letters

authors： Cloëz I,Bourre JM

更新日期：1987-12-16 00:00:00

abstract：:The neuron-specific phosphoprotein B-50 is a major substrate of kinase C in fetal nerve growth cones, neonatal neural and synaptosomal plasma membranes. B-50 is identical to a growth-associated protein GAP43. Similarly, increases in B-50 occur during rat brain development, neuronal differentiation and axon regeneratio...

journal_title：Neuroscience letters

authors： Gorgels TG,Oestreicher AB,de Kort EJ,Gispen WH

更新日期：1987-12-16 00:00:00

abstract：:Crayfish muscle fibres were voltage-clamped at E = -80 mV membrane potential and superfused for about 10 min with Li+ saline (Na+ replaced by Li+) which contained picrotoxin to block inhibitory post-synaptic currents. Addition of veratridine (100 mumol/l) caused intense fluctuations in the voltage clamp current within...

journal_title：Neuroscience letters

authors： Finger W,Martin C

更新日期：1987-12-16 00:00:00

abstract：:In all mammals so far investigated the occurrence of ponto-geniculo-occipital (PGO) waves precedes the onset and maintenance of desynchronized (D) sleep. As unitary electrographic events, PGO waves provide an index for quantitative evaluation of physiological D sleep or the D sleep-like state evoked by centrally admin...

journal_title：Neuroscience letters

authors： Baghdoyan HA,Lydic R,Callaway CW,Hobson JA

更新日期：1987-12-04 00:00:00

abstract：:In experiments using a synaptosomal preparation from the striatum and nucleus accumbens, somatostatin caused a dose-dependent increase in dopamine synthesis. This increase was additive with that produced by 8-BrcAMP but not with that produced by the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate (TPA), and was bl...

journal_title：Neuroscience letters

authors： Chowdhury M,Steardo L,Fillenz M

更新日期：1987-11-23 00:00:00

abstract：:To verify the hypothesis that the control of movement by the cortical masticatory area (CMA) is particularly important at the beginning of the mastication, we compared movements before and after bilateral CMA ablation. After ablation, the animal could not manipulate food placed in the front of the mouth for several da...

journal_title：Neuroscience letters

authors： Enomoto S,Schwartz G,Lund JP

更新日期：1987-11-23 00:00:00

abstract：:These experiments show that a synaptic response, namely the late inhibitory postsynaptic potential (IPSP) of hippocampal CA3 neurons of rats, is blocked by pertussis toxin, an inactivator of several GTP-binding proteins (G-proteins) excluding the G-protein that stimulates adenylyl cyclase. This blockage occurred witho...

journal_title：Neuroscience letters

authors： Thalmann RH

更新日期：1987-11-10 00:00:00

abstract：:The amino acid content of Torpedo synaptosomes was investigated. It was found that glutamate and taurine were particularly enriched, their concentration exceeding that of acetylcholine by 50-60%. Other amino acids such as alanine, gamma-aminobutyric acid (GABA), glycine, leucine and phenylalanine were also present, bu...

journal_title：Neuroscience letters

authors： Vyas S,Bradford HF

更新日期：1987-11-10 00:00:00

abstract：:The high-affinity, sodium-dependent uptake of dopamine (DA) was inhibited by the pretreatment of synaptosomes with neuraminidase from Vibrio cholerae. The inhibition was of a non-competitive type, resulting in a 40% decrease of Vmax. Neither basal nor depolarization-stimulated release of DA was affected. Treatment of ...

journal_title：Neuroscience letters

authors： Zaleska MM,Erecińska M

更新日期：1987-11-10 00:00:00

abstract：:Opioid kappa-agonists had much more potent inhibitory effects on the high K+-evoked Met-enkephalin release from rat brain slices than did the mu- or delta-agonists. The opioid kappa- antagonist, MR2266 enhanced the evoked release of Met-enkephalin to a greater extent than did mu- or delta-antagonists in vitro and had ...

journal_title：Neuroscience letters

authors： Ueda H,Fukushima N,Ge M,Takagi H,Satoh M

更新日期：1987-10-29 00:00:00

abstract：:Effect of 1-methyl-4-phenylpyridinium ion (MPP+) on adenosine triphosphate (ATP) synthesis was studied using isolated mitochondrial preparations from mouse brains. Oxidation of glutamate + malate in the mitochondria estimated by polarography was significantly inhibited by MPP+, and synthesis of ATP was inhibited to ap...

journal_title：Neuroscience letters

authors： Mizuno Y,Suzuki K,Sone N,Saitoh T

更新日期：1987-10-16 00:00:00

abstract：:Highly purified and metabolically viable gamma-aminobutyric acid (GABA)ergic and cholinergic synaptosomes were prepared from mammalian brain using antisera raised against glutamate decarboxylase and choline acetyltransferase respectively. These antisera appear to recognise specific outwardly facing components of GABAe...

journal_title：Neuroscience letters

authors： Docherty M,Bradford HF,Wu JY

更新日期：1987-10-16 00:00:00

abstract：:Tyrosine hydroxylase-like immunoreactive (TH-IR) neurons with morphological features of interneurons were found throughout the human cerebral cortex. Quantitative estimates in 14 different cytoarchitectonic areas revealed a specific regional distribution pattern, neurons being less dense in primary cortical areas and ...

journal_title：Neuroscience letters

authors： Gaspar P,Berger B,Febvret A,Vigny A,Krieger-Poulet M,Borri-Voltattorni C

更新日期：1987-10-05 00:00:00

abstract：:Purkinje cell degeneration (pcd) mutant mice lose cerebellar Purkinje cells. It was found that pcd mice, contrary to normal mice, did not alternate spontaneously at any of 3 inter-trial intervals (15 s, 3 or 6 min). Deficits in spontaneous alternation are typical of animals with brain damage in areas important in spat...

journal_title：Neuroscience letters

authors： Lalonde R,Manseau M,Botez MI

更新日期：1987-10-05 00:00:00

abstract：:The localization of substance P (SP) and calcitonin gene-related peptide (CGRP) was studied in the untreated spinal cord of the frog using single or double immunohistochemical stainings. SP and CGRP appear to coexist in the primary afferent fibers and in the marginal and submarginal dorsal horn zones, as well as in th...

journal_title：Neuroscience letters

authors： Venesio T,Mulatero B,Fasolo A

更新日期：1987-10-05 00:00:00

abstract：:Adenosine has been proposed to be a chemical link between cerebral metabolism and blood flow. In the present study, we investigated whether the intravenous or intracarotid administration of adenosine could influence regional cerebral blood flow in anesthetized rabbits. The study was performed with the [14C]ethanol tis...

journal_title：Neuroscience letters

authors： Puiroud S,Pinard E,Miller MC,Seylaz J

更新日期：1987-09-23 00:00:00

abstract：:The effects of stress on carcinogenesis have been equivocal. The present work examined the influence of an unpredictable pattern of chronic restraint stress on estradiol-induced pituitary hyperplasia in male Fischer 344 rats. The animals were grouped as follows: (1) control, (2) stressed, (3) estradiol (31 mg), subcut...

journal_title：Neuroscience letters

authors： Gottesfeld Z,Liehr JG

更新日期：1987-09-11 00:00:00

abstract：:Peptide histidine-isoleucine (PHI) immunoreactivity was located in amacrine-like cells in adult rat retina by use of immunohistochemical techniques. Immunoreactive somata were found in the proximal part of the inner nuclear layer. From these somata, processes could be followed into the inner plexiform layer. The termi...

journal_title：Neuroscience letters

authors： Mikkelsen JD,Larsen JN,Fahrenkrug J,Møller M

更新日期：1987-08-31 00:00:00

abstract：:Normal cerebellar tissue, obtained from 15-day-old CBA/JNCij mouse embryos, was transplanted into the cerebellum of 4-week-old weaver mice. At the 6th week after the transplantation, the grafted tissue was distinguishable from the host cerebellum, developing a trilaminar organization. The formation of synapses by the ...

journal_title：Neuroscience letters

authors： Takayama H,Kohsaka S,Shinozaki T,Inoue H,Toya S,Ueda T,Tsukada Y

更新日期：1987-08-31 00:00:00